Julkaisulista

Tältä sivulta löydät kaikki FinnGen-aineistoa hyödyntäneet julkaisut ja preprint-artikkelit.

2023

Elokuu

Machine learning reveals genetic modifiers of the immune microenvironment of cancer

Riley-Gillis B, Tsaih S-W, King E, Wollenhaupt S, Reeb J, Peck AR, Wackman K, Lemke A, Rui H, Dezso Z, Flister MJ.

iScience, Volume 26, Issue 9, 2023, 107576, ISSN 2589-0042, https://doi.org/10.1016/j.isci.2023.107576.

Genetically Proxied Sarcopenia-Related Muscle Traits and Depression: Evidence from the FinnGen Cohort

Lv Z, Zhao Y, Cui J, Zhang J.

Am J Geriatr Psychiatry. 2023 Aug 9:S1064-7481(23)00375-5. doi: 10.1016/j.jagp.2023.08.001

Genetic Evidence Strongly Supports Managing Weight and Blood Pressure in Addition to Glycemic Control in Preventing Vascular Complications in People With Type 2 Diabetes

Ahmed A, Amin H, Drenos F, Sattar N, Yaghootkar H.

Diabetes Care. 2023 Aug 9:dc230855. doi: 10.2337/dc23-0855.

A common variant that alters SUN1 degradation associates with hepatic steatosis and metabolic traits in multiple cohorts

Upadhyay KK, Du X, Chen Y, Buscher B, Chen VL, Oliveri A, Zhao R, Speliotes EK, Brady GF.

J Hepatol. 2023 Nov;79(5):1226-1235. doi: 10.1016/j.jhep.2023.07.036.

Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization

Woolf B, Cronjé HT, Zagkos L, Burgess S, Gill D, Larsson SC.

BMC Med. 2023 Aug 8;21(1):296. doi: 10.1186/s12916-023-03008-0.

Rheumatoid arthritis and heart failure: A bidirectional two-sample Mendelian randomization study

Yan Yang, Fenfang Cui, Min xu, Qin He, Ying Liu, Ying Lan, Xiqian Zhang, yaxian zheng, Xu Zhang

Researchsquare, 08 August 2023, doi: 10.21203/rs.3.rs-3227239/v1

Association between periodontitis and temporomandibular joint disorders

Wang S, Jiang H, Qi H, Luo D, Qiu T, Hu M.

Arthritis Res Ther. 2023 Aug 8;25(1):143. doi: 10.1186/s13075-023-03129-0.

Genetic Evidence for Causal Association Between Atrial Fibrillation and Dementia: A Mendelian Randomization Study

Li M, Jiang C, Lai Y, Wang Y, Zhao M, Li S, Peng X, He L, Guo X, Li S, Liu N, Jiang C, Tang R, Sang C, Long D, Du X, Dong J, Ma C.

J Am Heart Assoc. 2023 Aug 7:e029623. doi: 10.1161/JAHA.123.029623

Causal Roles of Lifestyle, Psychosocial Characteristics and Sleep Status in Sarcopenia: A Mendelian Randomization Study

Liu M, Yu D, Pan Y, Ji S, Han N, Yang C, Sun G.

J Gerontol A Biol Sci Med Sci. 2023 Aug 7:glad191. doi: 10.1093/gerona/glad191.

Genetically predicted childhood body mass index and lung cancer susceptibility: A two-sample Mendelian randomization study

Wu D, Zhou J, Huang Y, Zheng Q, Wang T, Liu L.

Cancer Med. 2023 Aug 7. doi: 10.1002/cam4.6406.

Genetically predicted thyroid function and risk of colorectal cancer: a bidirectional Mendelian randomization study

Du Q, Zheng Z, Wang Y, Yang L, Zhou Z.

J Cancer Res Clin Oncol. 2023 Aug 6. doi: 10.1007/s00432-023-05233-9.

A common genetic factor underlies genetic risk for gynaecological and reproductive disorders and is correlated with risk to depression

Kiewa J, Mortlock S, Meltzer-Brody S, Middeldorp C, Wray NR, Byrne EM.

Neuroendocrinology. 2023 Aug 4. doi: 10.1159/000533413.

The relationship between antidepressants and breast cancer: evidence from Mendelian randomization

Niu D, Li C, Yan X, Qu H, Zheng Y.

Cancer Causes Control. 2023 Aug 4. doi: 10.1007/s10552-023-01766-z.

Causal relationship between gut microbiome and risk of AMD: a two-sample Mendelian Randomization study

Gai-yun Li, Pei-sen Yao

Researchsquare, 04 August 2023, doi: 10.21203/rs.3.rs-3097550/v1

The relationship of fatty acids to ischaemic heart disease and lifespan in men and women using Mendelian randomization

Schooling CM, Kwok MK, Zhao JV.

Int J Epidemiol. 2023 Aug 3:dyad108. doi: 10.1093/ije/dyad108.

Combined CRISPRi and proteomics screening reveal a cohesin-CTCF-bound allele contributing to increased expression of RUVBL1 and prostate cancer progression

Tian Y, Dong D, Wang Z, Wu L, Park JY, Wei GH, Wang L; PRACTICAL/ELLIPSE consortium.

The American Journal of Human Genetics, Volume 110, Issue 8, 2023, https://doi.org/10.1016/j.ajhg.2023.07.003.

Univariable and multivariable Mendelian randomization investigating the effects of telomere length on the risk of adverse pregnancy outcomes.

Han X, Wu T, Liu CY.

Front Endocrinol (Lausanne). 2023 Aug 3;14:1225600. doi: 10.3389/fendo.2023.1225600.

A FinnGen pilot clinical recall study for Alzheimer's disease

Julkunen V, Schwarz C, Kalapudas J, Hallikainen M, Piironen AK, Mannermaa A, Kujala H, Laitinen T, Kosma VM, Paajanen TI, Kälviäinen R, Hiltunen M, Herukka SK, Kärkkäinen S, Kokkola T, Urjansson M; FinnGen; Perola M, Palotie A, Vuoksimaa E, Runz H.

Sci Rep. 2023 Aug 3;13(1):12641. doi: 10.1038/s41598-023-39835-7.

Rheumatoid arthritis and hypothyroidism: a bidirectional Mendelian randomization study.

Duan L, Chen D, Shi Y, Ye S, Dou S, Feng Y.

Front Immunol. 2023 Aug 2;14:1146261. doi: 10.3389/fimmu.2023.1146261

Tea Intake Increases Risk of Glaucoma: A Multivariable Mendelian Randomization Study

Changzhong Xu, Lusi Zhang, Guangshuang Tan, Datong Xu, Qian Jiang, Bing Jiang

Researchsquare, 02 August 2023, doi: 10.21203/rs.3.rs-3208832/v1

Two-sample Mendelian randomization study does not reveal a significant relationship between cytomegalovirus (CMV) infection and autism spectrum disorder

Zhang M, Ming Y, Du Y, Xin Z.

BMC Psychiatry. 2023 Aug 2;23(1):559. doi: 10.1186/s12888-023-05035-w.

Association between coffee consumption and diabetic complications: A two- sample Mendelian randomization study

Yingchao Liang, Xinyu Hu, Mingjie Jia, Deliang Liu, Shufang Chu, Huilin Li

Researchsquare, 01 August 2023, doi: 10.21203/rs.3.rs-3188194/v1

Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis

Tesfaye M, Jaholkowski P, Hindley GFL, Shadrin AA, Rahman Z, Bahrami S, Lin A, Holen B, Parker N, Cheng W, Rødevand L, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA.

Genome Med. 2023 Aug 1;15(1):60. doi: 10.1186/s13073-023-01212-4.

Genetic insights into the risk of metabolic syndrome and its components on psoriasis: A bidirectional Mendelian randomization

Liu L, Wang W, Si Y, Li X.

J Dermatol. 2023 Aug 1. doi: 10.1111/1346-8138.16910.

Causal association between basal metabolic rate and risk of cardiovascular diseases: a univariable and multivariable Mendelian randomization study

Li Y, Zhai H, Kang L, Chu Q, Zhao X, Li R.

Sci Rep. 2023 Aug 1;13(1):12487. doi: 10.1038/s41598-023-39551-2.

Heinäkuu

Genetically predicted osteoprotegerin levels and the risk of cardiovascular diseases: A Mendelian randomization study

Zhu Y, Wang Y, Wang Y, Cui Z, Liu F, Hu J.

Int J Cardiol. 2023 Jul 31:131233. doi: 10.1016/j.ijcard.2023.131233.

Causal relationship between osteoarthritis with atrial fibrillation and coronary atherosclerosis: a bidirectional Mendelian randomization study of European ancestry

Yin M, Xu W, Pang J, Xie S, Xiang M, Shi B, Fan H, Yu G.

Front Cardiovasc Med. 2023 Jul 31;10:1213672. doi: 10.3389/fcvm.2023.1213672.

Mendelian Randomisation Analysis Suggests that Hypothyroidism Reduces Endometrial Cancer Risk

Glubb DM, Wang X, O'Mara TA

medRxiv 2023.07.30.23293405; doi: https://doi.org/10.1101/2023.07.30.23293405

Genetic variation in SLC5A2 mimicking SGLT2-inhibition and risk of cardiovascular disease and all-cause mortality: reduced risk not explained by lower plasma glucose

Bechmann LE, Emanuelsson F, Nordestgaard BG, Benn M.

Cardiovasc Res. 2023 Jul 30:cvad122. doi: 10.1093/cvr/cvad122.

Immune-mediated inflammatory diseases and the risk of valvular heart disease: a Mendelian randomization study

Cai D, Zheng Z, Hu J, Fu Y, Song Y, Lian J.

Clin Rheumatol. 2023 Jul 28. doi: 10.1007/s10067-023-06693-7.

Association between the use of lipid-lowering drugs and the risk of inflammatory bowel disease

Liu X, Lv Z, Xie Z, Wang Q, Yao W, Yu J, Jing Q, Meng X, Ma B, Xue D, Hao C.

Eur J Clin Invest. 2023 Jul 28:e14067. doi: 10.1111/eci.14067.

Modifiable factors for benign salivary gland neoplasms: A Mendelian randomization study

Gao Y, Chen H, Liu Y, Zhang X, Qiu Y, Huang D.

Oral Dis. 2023 Jul 27. doi: 10.1111/odi.14682.

Genetic liability to multiple factors and uterine leiomyoma risk: a Mendelian randomization study

Qu Y, Chen L, Guo S, Liu Y, Wu H.

Front Endocrinol (Lausanne). 2023 Jul 27;14:1133260. doi: 10.3389/fendo.2023.1133260.

Causal Effects of Plasma Haptoglobin Levels on Alzheimer's Disease: A Two-Sample Mendelian Randomization Study

Lin Y, Hu T, Cheng L, Chen Y, Li W, Guo Q, Miao Y.

J Alzheimers Dis. 2023 Jul 26. doi: 10.3233/JAD-230159.

Genetic Variants Associated With Hidradenitis Suppurativa

Sun Q, Broadaway KA, Edmiston SN, Fajgenbaum K, Miller-Fleming T, Westerkam LL, Melendez-Gonzalez M, Bui H, Blum FR, Levitt B, Lin L, Hao H, Harris KM, Liu Z, Thomas NE, Cox NJ, Li Y, Mohlke KL, Sayed CJ.

JAMA Dermatol. 2023 Jul 26. doi: 10.1001/jamadermatol.2023.2217.

Bidirectional Mendelian Randomization and Multiphenotype GWAS Show Causality and Shared Pathophysiology Between Depression and Type 2 Diabetes

Maina JG, Balkhiyarova Z, Nouwen A, Pupko I, Ulrich A, Boissel M, Bonnefond A, Froguel P, Khamis A, Prokopenko I, Kaakinen M.

Diabetes Care 2023; dc222373. https://doi.org/10.2337/dc22-2373

Body mass index and risk of inflammatory breast disease: a Mendelian randomization study

Wei C, Wang X, Zeng J, Zhang G.

Nutr Hosp. 2023 Jul 26. English. doi: 10.20960/nh.04746.

No evidence of genetic causal association between sex hormone-related traits and systemic lupus erythematosus: A two-sample Mendelian randomization study

Yuan G, Yang M, Xie J, Xu K, Zhang F.

Clin Rheumatol. 2023 Jul 26. doi: 10.1007/s10067-023-06700-x.

The UK BiLEVE and Mendelian randomisation: using multivariable instrumental variables to address "damned if you, damned if you don't" adjustment problems

Woolf B, Gill D, Sallis H, Munafò MR.