Tältä sivulta löydät kaikki FinnGen-aineistoa hyödyntäneet julkaisut ja preprint-artikkelit.
2024

Huhtikuu

Associations between ticagrelor use and the risk of infections: A Mendelian randomization study
Xia M, Wu Q, Wang Y, Peng Y, Qian C.
J Infect Dis. 2024 Apr 8:jiae177. doi: 10.1093/infdis/jiae177.
Genetic causal relationship between immune diseases and migraine: a Mendelian randomization study
Li G, Duan S; International Headache Genetics Consortium (IHGC); Zheng T, Zhu T, Qu B, Liu L, Liu Z.
Front Immunol. 2024 Apr 8;15:1376698. doi: 10.3389/fimmu.2024.1376698.
Interplay Between Plasma Glycine and Branched-Chain Amino Acids Contributes to the Development of Hypertension and Coronary Heart Disease
Dziedzic M, Józefczuk E, Guzik TJ, Siedlinski M.
Hypertension. 2024 Apr 8. doi: 10.1161/HYPERTENSIONAHA.123.22649.
Identification of potential therapeutic targets for breast cancer using Mendelian randomization analysis and drug target prediction
Huang Z, Zheng H, Wang H, Ning H, Che A, Cai C.
Environ Toxicol. 2024 Apr 6. doi: 10.1002/tox.24249.
Sedentary lifestyle, physical activity, and gastrointestinal diseases: evidence from mendelian randomization analysis
Chen J, Ruan X, Fu T, Lu S, Gill D, He Z, Burgess S, Giovannucci EL, Larsson SC, Deng M, Yuan S, Li X.
EBioMedicine. 2024 Apr 6;103:105110. doi: 10.1016/j.ebiom.2024.105110.
Assessing the causal link between liver function and acute pancreatitis: A Mendelian randomisation study
Zhang C, Lin F, Guo DF, Wang QL, Xiao DX, Lin JY, Chen S.
PLoS One. 2024 Apr 5;19(4):e0300890. doi: 10.1371/journal.pone.0300890.
Love-hate relationship between hepatitis B virus and type 2 diabetes: a Mendelian randomization study
Yu Y, Tong K, Hu G, Yang X, Wu J, Bai S, Yu R.
Front Microbiol. 2024 Apr 5;15:1378311. doi: 10.3389/fmicb.2024.1378311.
Investigating genetic links between blood metabolites and preeclampsia
Lin Q, Li S, Wang H, Zhou W.
BMC Womens Health. 2024 Apr 5;24(1):223. doi: 10.1186/s12905-024-03000-7.
Causal associations of particulate matter 2.5 and cardiovascular disease: A two-sample mendelian randomization study
Cao Y, Feng Y, Xia N, Zhang J.
PLoS One. 2024 Apr 5;19(4):e0301823. doi: 10.1371/journal.pone.0301823.
Causality between cathepsins and idiopathic pulmonary fibrosis: a Mendelian randomization study
Zhuen Zhong, Ruochen Xu, Changhao Xu, Yanlin Zhu, Qian Xu, Yan Hua
Researchsquare, 05 April 2024, doi: 10.21203/rs.3.rs-4190026/v1
Serum albumin and cardiovascular disease: a Mendelian randomization study
Huang T, An Z, Huang Z, Gao W, Hao B, Xu J.
BMC Cardiovasc Disord. 2024 Apr 5;24(1):196. doi: 10.1186/s12872-024-03873-4.
Evaluation of the genetic architecture of human blood metabolites on sudden cardiac arrest: A Mendelian randomization analysis
Xisha Tang, Hui Jia Zhuang, Hai Yu
Researchsquare, 05 April 2024, doi: 10.21203/rs.3.rs-4011125/v1
No genetic causality between obesity and benign paroxysmal vertigo: A two-sample Mendelian randomization study
Guo Z, Huang B, Gan L, Liang S, Liu Y.
Open Med (Wars). 2024 Apr 5;19(1):20240940. doi: 10.1515/med-2024-0940.
Causal effect of gut microbiota on the risk of prostatitis: a two-sample Mendelian randomization study
Liu D, Mei Y, Ji N, Zhang B, Feng X.
Int Urol Nephrol. 2024 Apr 4. doi: 10.1007/s11255-024-04020-w.
Systematic proteome-wide Mendelian randomization using the human plasma proteome to identify therapeutic targets for lung adenocarcinoma
Zhang L, Xiong Y, Zhang J, Feng Y, Xu A.
J Transl Med. 2024 Apr 4;22(1):330. doi: 10.1186/s12967-024-04919-z.
Identification of prospective aging drug targets via Mendelian randomization analysis
Mao R, Li J, Xiao W.
Aging Cell. 2024 Apr 4:e14171. doi: 10.1111/acel.14171.
Identification of potential drug targets for allergic diseases from a genetic perspective: A mendelian randomization study
Wang H, Pang J, Zhou Y, Qi Q, Tang Y, Gul S, Sheng M, Dan J, Tang W.
Clin Transl Allergy. 2024 Apr;14(4):e12350. doi: 10.1002/clt2.12350.
Potential benefits of statin therapy in reducing osteoarthritis risk: a Mendelian randomization study
Zhang L, Sui L, Li J, Zhang R, Pan W, Lv T.
Arthritis Care Res (Hoboken). 2024 Apr 3. doi: 10.1002/acr.25343.
Ancestral allele of DNA polymerase gamma modifies antiviral tolerance
Kang Y, Hepojoki J, Maldonado RS, Mito T, Terzioglu M, Manninen T, Kant R, Singh S, Othman A, Verma R, Uusimaa J, Wartiovaara K, Kareinen L, Zamboni N, Nyman TA, Paetau A, Kipar A, Vapalahti O, Suomalainen A.
Nature. 2024 Apr;628(8009):844-853. doi: 10.1038/s41586-024-07260-z.
Genetic predisposition to childhood obesity does not influence the risk of developing skin cancer in adulthood
Keatley J, Law MH, Seviiri M, Olsen CM, Pandeya N, Ong JS, MacGregor S, Whiteman DC, Dusingize JC.
Sci Rep. 2024 Apr 3;14(1):7854. doi: 10.1038/s41598-024-58418-8.
Shared genetic etiology between hypothyroidism and complex diseases: a large-scale genome-wide cross-trait analysis
Li S, Gong M.
medRxiv 2024.04.02.24305135; doi: https://doi.org/10.1101/2024.04.02.24305135
Roles of gut microbiota in androgenetic alopecia: insights from Mendelian randomization analysis
Fu H, Xu T, Zhao W, Jiang L, Shan S.
Front Microbiol. 2024 Apr 2;15:1360445. doi: 10.3389/fmicb.2024.1360445.
Diet-derived circulating antioxidants, periodontitis and dental caries: A Mendelian randomization study
Gao Y, Huang D, Liu Y, Qiu Y, Lu S.
J Periodontal Res. 2024 Apr 2. doi: 10.1111/jre.13260.
Role of CD64 on CD14+ CD16+ Monocytes in Mediating the Effect of genus Collinsella on Nonalcoholic Fatty Liver Disease
Ru yi Yu, Guoyong Chen, dong xia
Researchsquare, 02 April 2024, doi: 10.21203/rs.3.rs-4146688/v1
Exploring Potential Drug Targets for Pancreatic Cancer Based on Mendelian Randomization
Peishan Yao, junming huang, yi dang, Ya Wang
Researchsquare, 02 April 2024, doi: 10.21203/rs.3.rs-4183057/v1
Dual effects of serum urate on stroke risk and prognosis: insights from Mendelian randomization
Chen S, Chen Z, Xu Q, Jiang X, Lin C, Ji J.
Front Neurol. 2024 Apr 2;15:1359292. doi: 10.3389/fneur.2024.1359292.
Genetic determinants of plasma protein levels in the Estonian population
Kalnapenkis A, Jõeloo M, Lepik K, Kukuškina V, Kals M, Alasoo K; Estonian Biobank Research Team; Mägi R, Esko T, Võsa U.
Sci Rep. 2024 Apr 2;14(1):7694. doi: 10.1038/s41598-024-57966-3.
Genetic associations of protein-coding variants in venous thromboembolism
He XY, Wu BS, Yang L, Guo Y, Deng YT, Li ZY, Fei CJ, Liu WS, Ge YJ, Kang J, Feng J, Cheng W, Dong Q, Yu JT.
Nat Commun. 2024 Apr 1;15(1):2819. doi: 10.1038/s41467-024-47178-8.
The causal relationship between COVID-19 and ten esophageal diseases: a study utilizing Mendelian randomization
He X, Li Y, Liu J, Yan G, Gao X, Li G, Wei L, Feng G, Li J, Zhou H.
Front Med (Lausanne). 2024 May 1;11:1346888. doi: 10.3389/fmed.2024.1346888.
A Mendelian randomization study of the effect of selenium on autoimmune thyroid disease
Hu C, Yu YF, Tong KK, Hu G, Wu JY, Yang XY, Bai SY, Yu R, Li YY.
Eur Rev Med Pharmacol Sci. 2024 Apr;28(8):2988-2995. doi: 10.26355/eurrev_202404_36011.

Maaliskuu

The Impact of Non-alcohol Fatty Liver Disease on Bone Mineral Density is Mediated by Sclerostin by Mendelian Randomization Study
Liu Y, Yuan M, He J, Cai L, Leng A.
Calcif Tissue Int. 2024 May;114(5):502-512. doi: 10.1007/s00223-024-01204-5.
Genetically determined metabolites in allergic conjunctivitis: A Mendelian randomization study
Zou X, Huang H, Tan Y.
World Allergy Organ J. 2024 Mar 31;17(4):100894. doi: 10.1016/j.waojou.2024.100894.
Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
Wu Y, Qian Q, Liu Q, Wang R, Pu X, Li Y, Zhang H, You Z, Miao Q, Xiao X, Lian M, Wang Q, Nakamura M, Gershwin ME, Li Z, Ma X, Tang R.
Clin Rev Allergy Immunol. 2024 Mar 30. doi: 10.1007/s12016-024-08986-4.
The role of genetically-influenced phospholipid transfer protein activity in lipoprotein metabolism and coronary artery disease
Ao L, Noordam R, Rensen PCN, van Heemst D, Willems van Dijk K.
J Clin Lipidol. 2024 Jul-Aug;18(4):e579-e587. doi: 10.1016/j.jacl.2024.03.007.
Assessment of bidirectional relationships between autoimmune diseases and primary ovarian insufficiency: insights from a bidirectional two-sample Mendelian randomization analysis
Luo R, Wang J, Liu Y.
Arch Gynecol Obstet. 2024 Mar 29. doi: 10.1007/s00404-024-07482-6.
Pharmaceutical Repurposing Strategies for Metabolic Disorders: Insights from Mendelian Randomization Studies
Zhang S, Hu X, Hou D, Sun X, Sun D.
medRxiv 2024.03.29.24305070; doi: https://doi.org/10.1101/2024.03.29.24305070
Genetic Associations of Primary Angle-Closure Disease: A Systematic Review and Meta-Analysis
Liang YJ, Wang YY, Rong SS, Chen ZJ, Chen SY, Tham JA, Chan PP, Yam JC, Wiggs JL, Pang CP, Tham CC, Chen LJ.
JAMA Ophthalmol. 2024 Mar 28:e240363. doi: 10.1001/jamaophthalmol.2024.0363.
Association between asthma and melanoma: Results from the NHANES 2009-2016 and Mendelian randomization study
Jun Tan, Xuanran Huang, Yan Dong, Jianjun Li
Researchsquare, 28 March 2024, doi: 10.21203/rs.3.rs-4144117/v1
The causal effect of iron status on risk of anxiety disorders: A two-sample Mendelian randomization study
Yin R, Gao Q, Fu G, Zhao Q.
PLoS One. 2024 Mar 28;19(3):e0300143. doi: 10.1371/journal.pone.0300143.
Association of circulating inflammatory proteins with type 2 diabetes mellitus and its complications: a bidirectional Mendelian randomization study
Liang YC, Jia MJ, Li L, Liu DL, Chu SF, Li HL.
Front Endocrinol (Lausanne). 2024 Mar 28;15:1358311. doi: 10.3389/fendo.2024.1358311.
Mendelian Randomization Highlights Gut Microbiota of Short-chain Fatty Acids' Producer as Protective Factor of Cerebrovascular Disease
Luo S, Mao R, Li Y.
Curr Neurovasc Res. 2024 Mar 28. doi: 10.2174/0115672026299307240321090030.
Evaluation of Plasma Biomarkers for Causal Association With Peripheral Artery Disease
Sharma P, Klarin D, Voight BF, Tsao PS, Levin MG, Damrauer SM.
Arterioscler Thromb Vasc Biol. 2024 Mar 28. doi: 10.1161/ATVBAHA.124.320674.
Causal Relationship between the Gut Microbiota and Haematological Malignancies: A Two-Sample Mendelian Randomization Analysis
Biyu Xiang, Qianyuan Li, Hongfei Zhang, Shuqi JI, Yuzhen Peng, Chenjiao Yao
Researchsquare, 28 March 2024, doi: 10.21203/rs.3.rs-4124452/v1
Association between asthma and melanoma: Results from the NHANES 2009-2016 and Mendelian randomization study
Jun Tan, Xuanran Huang, Yan Dong, Jianjun Li
Researchsquare, 28 March 2024, doi: 10.21203/rs.3.rs-4144117/v1
Association between gut microbiota and autoimmune cholestatic liver disease, a Mendelian randomization study
Cui Y, Guo Y, Kong Y, Zhang G.
Front Microbiol. 2024 Mar 27;15:1348027. doi: 10.3389/fmicb.2024.1348027.
Complex interplay of neurodevelopmental disorders (NDDs), fractures, and osteoporosis: a mendelian randomization study
Li Z, Wu X, Li H, Bi C, Zhang C, Sun Y, Yan Z.
BMC Psychiatry. 2024 Mar 27;24(1):232. doi: 10.1186/s12888-024-05693-4.
Genetic associations between circulating immune cells and periodontitis highlight the prospect of systemic immunoregulation in periodontal care
Ye X, Bai Y, Li M, Ye Y, Chen Y, Liu B, Dai Y, Wang S, Pan W, Wang Z, Mao Y, Chen Q.
Elife. 2024 Mar 27;12:RP92895. doi: 10.7554/eLife.92895.
Metformin treatment reduces the incidence of osteoporosis: a two-sample Mendelian randomized study
Cai Y, Jun G, Zhuang X.
Osteoporos Int. 2024 Jun;35(6):1089-1098. doi: 10.1007/s00198-023-07013-0.
Genetic risk, adherence to healthy lifestyle behaviors, and risk of cholelithiasis: A population-based cohort study
Mi N, Liang Z, Yang M, Zhao J, Tian L, Huang C, Xie P, Wu S, He Q, Sun Y, Lin Y, Yue P, Xia B, Yuan J, Meng W.
Prev Med. 2024 Mar 27;182:107942. doi: 10.1016/j.ypmed.2024.107942.
Causal relationship between immune cells and Osteonecrosis: a bidirectional Mendelian randomization study
Chen meng, Baochuang Qi, Huan Luo, Zhifang Tang, Junxiao Ren, Hongxin Shi, Chuan Li, Yongqing Xu
Researchsquare, 27 March 2024, doi:10.21203/rs.3.rs-4137998/v1