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Single-cell transcriptome integrated with genome-wide association study reveals heterogeneity of carotid and femoral plaques and its association with plaque stability

Submitted by Frida Mäkelä on Mon, 07/14/2025 - 13:42
  • Read more about Single-cell transcriptome integrated with genome-wide association study reveals heterogeneity of carotid and femoral plaques and its association with plaque stability

Exploring causal relationships between circulating micronutrients and age-related eye diseases: a Mendelian randomization study

Submitted by Frida Mäkelä on Mon, 07/14/2025 - 13:36
  • Read more about Exploring causal relationships between circulating micronutrients and age-related eye diseases: a Mendelian randomization study

Complex interplay between type 2 diabetes mellitus and pancreatic cancer: insights from observational and mendelian randomization analyses

Submitted by Frida Mäkelä on Mon, 07/14/2025 - 13:31
  • Read more about Complex interplay between type 2 diabetes mellitus and pancreatic cancer: insights from observational and mendelian randomization analyses

Exploring new drug treatment targets for immune related bone diseases using a multi omics joint analysis strategy

Submitted by Frida Mäkelä on Mon, 07/14/2025 - 13:27
  • Read more about Exploring new drug treatment targets for immune related bone diseases using a multi omics joint analysis strategy

Immune cell phenotypes as causal factors in liver disease progression revealed by Mendelian randomization

Submitted by Frida Mäkelä on Mon, 07/14/2025 - 13:21
  • Read more about Immune cell phenotypes as causal factors in liver disease progression revealed by Mendelian randomization

PM2.5 increases the risk of early-onset COPD mediated by smoking and shared genes: a large-scale genetic analysis

Submitted by Frida Mäkelä on Mon, 07/14/2025 - 13:08
  • Read more about PM2.5 increases the risk of early-onset COPD mediated by smoking and shared genes: a large-scale genetic analysis

Telomere Length, Brain Imaging-Derived Phenotypes, and Alzheimer’s Disease: Mendelian Randomization Analysis

Submitted by Frida Mäkelä on Mon, 07/14/2025 - 13:04
  • Read more about Telomere Length, Brain Imaging-Derived Phenotypes, and Alzheimer’s Disease: Mendelian Randomization Analysis

Association between mental disorders and trigeminal neuralgia: a cohort study and Mendelian randomization analysis

Submitted by Frida Mäkelä on Mon, 07/14/2025 - 12:56
  • Read more about Association between mental disorders and trigeminal neuralgia: a cohort study and Mendelian randomization analysis

TLR4 identified as a major depressive disorder gene signature mediating effects through multiple immune cells

Submitted by Frida Mäkelä on Mon, 07/14/2025 - 12:51
  • Read more about TLR4 identified as a major depressive disorder gene signature mediating effects through multiple immune cells

Identifying Potential Drug Targets in Coronary Atherosclerosis: Insights from the Druggable Genome and Mendelian Randomization

Submitted by Frida Mäkelä on Mon, 07/14/2025 - 11:52
  • Read more about Identifying Potential Drug Targets in Coronary Atherosclerosis: Insights from the Druggable Genome and Mendelian Randomization

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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