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Identification of MMEL1 as a novel therapeutic target for primary sclerosing cholangitis: Integrating Mendelian randomization and transcriptome landscapes

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Submitted by Anna Hakala on Tue, 10/07/2025 - 09:40
  • Read more about Identification of MMEL1 as a novel therapeutic target for primary sclerosing cholangitis: Integrating Mendelian randomization and transcriptome landscapes

Genetic evidence for the effect of prepregnancy maternal metabolic status on the risk of congenital heart disease in offspring: A Mendelian randomization study

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Submitted by Anna Hakala on Tue, 10/07/2025 - 09:39
  • Read more about Genetic evidence for the effect of prepregnancy maternal metabolic status on the risk of congenital heart disease in offspring: A Mendelian randomization study

Two-sample Mendelian randomization investigating the causal association between endocarditis and osteomyelitis: A validation analysis using UK Biobank and FinnGen databases

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Submitted by Anna Hakala on Tue, 10/07/2025 - 09:36
  • Read more about Two-sample Mendelian randomization investigating the causal association between endocarditis and osteomyelitis: A validation analysis using UK Biobank and FinnGen databases

Limited overlap between genetic effects on disease susceptibility and disease survival

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Submitted by Anna Hakala on Tue, 10/07/2025 - 09:33
  • Read more about Limited overlap between genetic effects on disease susceptibility and disease survival

Association between mitochondrial DNA copy number and the risk of Parkinson's disease: a meta-analysis and Mendelian randomization study

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Submitted by Anna Hakala on Tue, 10/07/2025 - 09:31
  • Read more about Association between mitochondrial DNA copy number and the risk of Parkinson's disease: a meta-analysis and Mendelian randomization study

Multiomic Mendelian randomization analysis of metabolic gene methylation expression and protein levels in lung adenocarcinoma

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Submitted by Anna Hakala on Tue, 10/07/2025 - 09:26
  • Read more about Multiomic Mendelian randomization analysis of metabolic gene methylation expression and protein levels in lung adenocarcinoma

Association between brain connectivity and renal pathophysiology: a multi-trait Mendelian randomization analysis

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Submitted by Anna Hakala on Tue, 10/07/2025 - 09:22
  • Read more about Association between brain connectivity and renal pathophysiology: a multi-trait Mendelian randomization analysis

Exploring Causal Relationships Between Kidney Function and the Risk of Senile Cataract and Primary Open-Angle Glaucoma: A Mendelian Randomization Study and Bioinformatics Analyses

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Submitted by Anna Hakala on Tue, 10/07/2025 - 09:20
  • Read more about Exploring Causal Relationships Between Kidney Function and the Risk of Senile Cataract and Primary Open-Angle Glaucoma: A Mendelian Randomization Study and Bioinformatics Analyses

Genetic liability to meniscus degeneration and its comorbidity patterns: a phenome-wide association study in the UK Biobank

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Submitted by Anna Hakala on Tue, 10/07/2025 - 09:06
  • Read more about Genetic liability to meniscus degeneration and its comorbidity patterns: a phenome-wide association study in the UK Biobank

FINEMAP-miss: Fine-mapping genome-wide association studies with missing genotype information

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Submitted by Anna Hakala on Tue, 10/07/2025 - 08:55
  • Read more about FINEMAP-miss: Fine-mapping genome-wide association studies with missing genotype information

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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