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Genetic Assessment of Oesophageal Safety of GLP-1 and GIP Receptor Perturbation: A Drug-Target Mendelian Randomisation Study

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Submitted by Anna Hakala on Mon, 09/28/2026 - 10:58
  • Read more about Genetic Assessment of Oesophageal Safety of GLP-1 and GIP Receptor Perturbation: A Drug-Target Mendelian Randomisation Study

Protective effects of sarcopenia-related traits on spinal degenerative diseases: A large prospective cohort study

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Submitted by Anna Hakala on Mon, 09/28/2026 - 10:57
  • Read more about Protective effects of sarcopenia-related traits on spinal degenerative diseases: A large prospective cohort study

Identification of CA2 as a potential candidate gene involved in the therapeutic effect of Huatan Huoxue decoction on polycystic ovary syndrome: An integrated study of network pharmacology, Mendelian randomization, and experimental validation

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Submitted by Anna Hakala on Mon, 09/28/2026 - 10:56
  • Read more about Identification of CA2 as a potential candidate gene involved in the therapeutic effect of Huatan Huoxue decoction on polycystic ovary syndrome: An integrated study of network pharmacology, Mendelian randomization, and experimental validation

Mapping Cell-Type-Specific Regulatory Variants in Vascular Dementia by Integrating Single-Cell Chromatin Accessibility and Gene Expression

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Submitted by Anna Hakala on Mon, 09/28/2026 - 10:55
  • Read more about Mapping Cell-Type-Specific Regulatory Variants in Vascular Dementia by Integrating Single-Cell Chromatin Accessibility and Gene Expression

Genetic Prioritization of Plasma Proteins Across Dementia Subtypes: A Proteome-Wide Mendelian Randomization and Bayesian Colocalization Analysis

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Submitted by Anna Hakala on Mon, 09/28/2026 - 10:54
  • Read more about Genetic Prioritization of Plasma Proteins Across Dementia Subtypes: A Proteome-Wide Mendelian Randomization and Bayesian Colocalization Analysis

The Effect of PTPN22 Polymorphism on Juvenile Idiopathic Arthritis Subtypes and Disease Activity in a Finnish Study Population

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Submitted by Anna Hakala on Mon, 09/28/2026 - 10:54
  • Read more about The Effect of PTPN22 Polymorphism on Juvenile Idiopathic Arthritis Subtypes and Disease Activity in a Finnish Study Population

Circulating proteins as key genetically proxied mediators in the pathway from smoking to intracranial aneurysm disease: A mediation Mendelian randomization analysis

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Submitted by Anna Hakala on Mon, 09/28/2026 - 10:53
  • Read more about Circulating proteins as key genetically proxied mediators in the pathway from smoking to intracranial aneurysm disease: A mediation Mendelian randomization analysis

Genetically informed prioritization of immune checkpoint-associated genes in head and neck cancer highlights HGF and AKT1

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Submitted by Anna Hakala on Mon, 09/28/2026 - 10:52
  • Read more about Genetically informed prioritization of immune checkpoint-associated genes in head and neck cancer highlights HGF and AKT1

Exploratory bidirectional Mendelian randomisation analysis of cerebrospinal fluid metabolites associated with cerebral palsy and epilepsy

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Submitted by Anna Hakala on Mon, 09/28/2026 - 10:52
  • Read more about Exploratory bidirectional Mendelian randomisation analysis of cerebrospinal fluid metabolites associated with cerebral palsy and epilepsy

Genetically Predicted Intervertebral Disc Degeneration and Risk of Osteoarthritis: A Two-Sample Mendelian Randomization Study with Mediation Analysis of Obesity and Sarcopenia

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Submitted by Anna Hakala on Mon, 09/28/2026 - 10:51
  • Read more about Genetically Predicted Intervertebral Disc Degeneration and Risk of Osteoarthritis: A Two-Sample Mendelian Randomization Study with Mediation Analysis of Obesity and Sarcopenia

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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