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Genetically Proxied Interleukin-6 Inhibition and Cancer Risk: A Multi-Ancestry Drug-Target Mendelian Randomization Study of Hepatocellular Carcinoma and Colorectal Cancer

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Submitted by Anna Hakala on Tue, 06/30/2026 - 14:04
  • Read more about Genetically Proxied Interleukin-6 Inhibition and Cancer Risk: A Multi-Ancestry Drug-Target Mendelian Randomization Study of Hepatocellular Carcinoma and Colorectal Cancer

Genetically predicted lower FLT3L levels increase the risk of hypertrophic cardiomyopathy partly mediated by phosphate: Evidence from a 2-step Mendelian randomization analysis

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Submitted by Anna Hakala on Tue, 06/30/2026 - 13:04
  • Read more about Genetically predicted lower FLT3L levels increase the risk of hypertrophic cardiomyopathy partly mediated by phosphate: Evidence from a 2-step Mendelian randomization analysis

Genetically predicted childhood traits and parental health and risk of pediatric psychiatric disorders: A 2-sample Mendelian randomization study

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Submitted by Anna Hakala on Tue, 06/30/2026 - 13:03
  • Read more about Genetically predicted childhood traits and parental health and risk of pediatric psychiatric disorders: A 2-sample Mendelian randomization study

Fine-Mapping of HLA Effects in Oral and Non-Oral Lichen Planus

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Submitted by Anna Hakala on Tue, 06/30/2026 - 12:53
  • Read more about Fine-Mapping of HLA Effects in Oral and Non-Oral Lichen Planus

FES suppresses macrophage-mediated inflammation and atherosclerotic plaque formation by modulating the PU.1/Arg1 axis

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Submitted by Anna Hakala on Tue, 06/30/2026 - 12:52
  • Read more about FES suppresses macrophage-mediated inflammation and atherosclerotic plaque formation by modulating the PU.1/Arg1 axis

Insulin Resistance-Related Traits and Diabetic Maculopathy: Causal Insights from Mendelian Randomization

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Submitted by Anna Hakala on Tue, 06/30/2026 - 12:51
  • Read more about Insulin Resistance-Related Traits and Diabetic Maculopathy: Causal Insights from Mendelian Randomization

Dissecting the shared genetic architecture between migraine subtypes and cardiovascular diseases: a multi-layered genomic analysis

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Submitted by Anna Hakala on Mon, 06/29/2026 - 16:57
  • Read more about Dissecting the shared genetic architecture between migraine subtypes and cardiovascular diseases: a multi-layered genomic analysis

Mendelian Randomization Analysis of Systemic Iron Status and Risk of Metabolic Dysfunction-Associated Steatotic Liver Disease

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Submitted by Anna Hakala on Mon, 06/29/2026 - 16:55
  • Read more about Mendelian Randomization Analysis of Systemic Iron Status and Risk of Metabolic Dysfunction-Associated Steatotic Liver Disease

Differential Causal Associations of Gut Microbiota, Blood Metabolites, and Immune Cell Phenotypes With Early- and Late-Onset Alzheimer's Disease: A Bidirectional Mendelian Randomization Analysis

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Submitted by Anna Hakala on Mon, 06/29/2026 - 16:54
  • Read more about Differential Causal Associations of Gut Microbiota, Blood Metabolites, and Immune Cell Phenotypes With Early- and Late-Onset Alzheimer's Disease: A Bidirectional Mendelian Randomization Analysis

Peripheral B cell immune dysregulation genetically contributes to stage-dependent neuroinflammation and identifies priority therapeutic targets in Parkinson's disease: a computational integration of Mendelian randomization and single-cell transcriptomics

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Submitted by Anna Hakala on Mon, 06/29/2026 - 16:52
  • Read more about Peripheral B cell immune dysregulation genetically contributes to stage-dependent neuroinflammation and identifies priority therapeutic targets in Parkinson's disease: a computational integration of Mendelian randomization and single-cell transcriptomics

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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