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Multi-cohort and single-nucleus transcriptomics identify a five-gene lactylation-related panel and a disease-dependent hepatocyte glycolysis-lactylation-related expression program in metabolic dysfunction-associated steatohepatitis

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Submitted by Anna Hakala on Mon, 11/02/2026 - 12:03
  • Read more about Multi-cohort and single-nucleus transcriptomics identify a five-gene lactylation-related panel and a disease-dependent hepatocyte glycolysis-lactylation-related expression program in metabolic dysfunction-associated steatohepatitis

Dissecting cell-type-specific genetic associations between colorectal cancer liability and thrombotic risk in peripheral blood immune cells

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Submitted by Anna Hakala on Mon, 11/02/2026 - 12:02
  • Read more about Dissecting cell-type-specific genetic associations between colorectal cancer liability and thrombotic risk in peripheral blood immune cells

Integrative Multiomics Mendelian Randomization Prioritizes Endoplasmic Reticulum Stress-Related Genes Associated With Gastric Cancer Risk

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Submitted by Anna Hakala on Mon, 11/02/2026 - 12:02
  • Read more about Integrative Multiomics Mendelian Randomization Prioritizes Endoplasmic Reticulum Stress-Related Genes Associated With Gastric Cancer Risk

A Genome-Wide Association Study Identifies Novel Genetic Variants Associated with Knee Pain in the UK Biobank (n = 439,743)

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Submitted by Anna Hakala on Mon, 11/02/2026 - 12:01
  • Read more about A Genome-Wide Association Study Identifies Novel Genetic Variants Associated with Knee Pain in the UK Biobank (n = 439,743)

Cell-type-resolved colocalisation prioritises KCNIP2 as a candidate epilepsy drug-target detectable at inhibitory-neuron but not bulk-tissue resolution: a Mendelian randomisation and colocalisation study

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Submitted by Anna Hakala on Mon, 11/02/2026 - 12:00
  • Read more about Cell-type-resolved colocalisation prioritises KCNIP2 as a candidate epilepsy drug-target detectable at inhibitory-neuron but not bulk-tissue resolution: a Mendelian randomisation and colocalisation study

Integrated Single-Cell Transcriptomics, Multi-Omics, and Mendelian Randomization Reveal Ferroptosis-Related Molecular Subtypes and a Genetically Supported Causal Candidate in Psoriasis

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Submitted by Anna Hakala on Mon, 11/02/2026 - 11:57
  • Read more about Integrated Single-Cell Transcriptomics, Multi-Omics, and Mendelian Randomization Reveal Ferroptosis-Related Molecular Subtypes and a Genetically Supported Causal Candidate in Psoriasis

Genetic liability to systemic lupus erythematosus and autoimmune thyroid diseases: evidence from a bidirectional mendelian randomization study

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Submitted by Anna Hakala on Mon, 11/02/2026 - 11:56
  • Read more about Genetic liability to systemic lupus erythematosus and autoimmune thyroid diseases: evidence from a bidirectional mendelian randomization study

Identification of Genes Associated with Gut Microbiota Metabolites in Type 2 Diabetes Mellitus Complicated by Acute Cerebral Infarction Based on Bioinformatics and Mendelian Randomization

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Submitted by Anna Hakala on Mon, 11/02/2026 - 11:55
  • Read more about Identification of Genes Associated with Gut Microbiota Metabolites in Type 2 Diabetes Mellitus Complicated by Acute Cerebral Infarction Based on Bioinformatics and Mendelian Randomization

Genetically Predicted Circulating Lipid Traits and Risk of Primary Open-Angle Glaucoma: A Mendelian Randomization Study

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Submitted by Anna Hakala on Mon, 11/02/2026 - 11:53
  • Read more about Genetically Predicted Circulating Lipid Traits and Risk of Primary Open-Angle Glaucoma: A Mendelian Randomization Study

Associations of Blood Lipid Traits with Cognitive-Related Outcomes and Their Sensitivity to APOE-Region Instrumental Variables: A Mendelian Randomization and Colocalization Study

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Submitted by Anna Hakala on Mon, 11/02/2026 - 11:52
  • Read more about Associations of Blood Lipid Traits with Cognitive-Related Outcomes and Their Sensitivity to APOE-Region Instrumental Variables: A Mendelian Randomization and Colocalization Study

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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